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EXOE Ona product photo

Exo|e is a cutting-edge, regenerative medical skincare treatment protocol, available in Nashville, TN. Derived from stem cells and used to promote natural healing and regeneration, these products’ complex exosomes can help alleviate inflammation, accelerate wound healing and rejuvenate skin.

Exo|e Skin Revitalizing Complex

What is Exo|e?

Reasons to use EXOE infographicExo|e plant stem cell technology applies nanoparticle technology and biomimetics to the science of beauty. Exosomes are naturally found in the human body, where they play a crucial role in cell-to-cell signaling. They carry lipids, proteins and enzymes to damaged areas, hastening intercellular communication for faster recovery, repair and regeneration.

Exosomes have a high concentration of stem cell factors, including liposomes, anti-inflammatory factors, peptides and growth factors which all aid in tissue repair.

For skin rejuvenation, Exo|e stimulates the production of skin-rejuvenating factors like collagen, hyaluronic acid and elastin. Treatment with Exo|e can help manage severe acne, facilitate wound healing and supply the skin with much-needed hydration. As exosomes correspond to what your skin needs, this treatment can be used in combination with energy-based therapies or microneedling.

Am I a Good Candidate?

Exo|e may be suitable for individuals seeking a non-surgical, minimally-invasive treatment option for skin rejuvenation. If you want to reduce the early signs of aging, you’re an ideal candidate for Exo|e. You may also be recommended for Exo|e therapy if you have rosacea or hyperpigmentation. Patients must not have an active infection in the targeted areas.

Your Consultation

A skin examination will be performed during your consultation for Exo|e treatment. An assessment of your overall skin health and a review of your medical history will be conducted. You will be given more information about the treatment so you can make an informed decision.


At Ona Skincare

“Small, quiet, intimate, comfy and serene. I have been a client of Melissa Rhodes RN for years now. I refer all my clients and friends to her as well. She takes care of my facial Peels and everything needle. Pricing is competitive to market. Most importantly, I can trust her, she really knows what she’s doing.”– Renee B.

Consultation to Maintenance Process Infographic

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The Procedure

EXOE Before and After Photo by Ona Skincare in Nashville, TNThe protocol for Exo|e application involves three steps for topical application. No special preparation is required beforehand.

D|tox is provided after the consultation session, to be applied prior to your in-office treatment. This product will prepare your skin for exosome therapy by helping skin to minimize any anti-inflammatory response for faster healing. You will apply it twice daily for five days to targeted areas of the skin, post-cleansing—once in the morning and once at night.

Exo|e treatment is performed during an in-office visit. It can be applied on its own, or it can be applied prior to, or after, any combination treatments you may receive, as recommended by your medical skincare specialist. It is massaged onto your face and remains applied for 15 minutes to allow for optimal absorption.

Re|Pair is provided following the exosome treatment. You will be instructed to apply it on the treated areas twice daily. During this phase, you should discontinue use of any other skincare products.


The treatment is generally well-tolerated, and most patients are able to immediately return to their normal routine. You may need downtime only if exosome therapy is combined with other treatments, such as ablative laser treatment or microneedling.

How Much Does Exo|e Cost?

The cost of Exo|e varies due to individual patient needs. The overall price may be impacted by the timeline of the treatment and amount of product needed.

Arrange a Consultation

Discover the incredible skin-rebalancing and rejuvenation benefits of Exo|e in Nashville. Contact Ona Skincare today to schedule your consultation.